CCSVI is a condition called "Chronic Cerebrospinal Venous Insufficiency" and was discovered by Dr. Paolo Zamboni, a vascular surgeon at the University of Ferrara in Italy. It refers to a narrowing or blockage of the primary veins draining blood from the brain to the heart. These include the jugular veins, veins along the spinal column and the azygos vein in the upper chest.